#2 Limited access of CAR-T cells to solid tumours
So far it has proven a challenge to deliver clinically effective doses of CAR-T cells to solid tumours or resection (after surgery) sites. One of the issues to overcome is
The structure of a CAR construct
CHIMERIC ANTIGEN RECEPTORS (CARs) ARE HUMAN-MADE MOLECULES EXPRESSED ON THE SURFACE OF T CELLS, KEY CELLS OF THE IMMUNE SYSTEM These CARs are targeted at markers on cancer cells. T