About carbio

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So far carbio has created 23 blog entries.

Third-generation CARs

2018-09-07T15:59:42+09:30September 7th, 2015|timeline|

Third-generation CAR molecules were produced by incorporating two or more co-stimulatory molecules into the CAR construct. These CARs are not necessarily more superior than second-generation (results from comparative studies are

In 2014

2018-09-07T16:02:29+09:30September 7th, 2014|timeline|

In 2014 CAR-T therapy received Breakthrough Drug designation from the US Food and Drug Administration for relapsed and/or refractory acute lymphoblastic leukaemia.

Late 1990s …

2018-09-07T16:09:39+09:30September 7th, 1998|timeline|

In the late 1990s it was found that CARs would be more effective if they were designed with the addition of another molecule - a ‘co-stimulatory’ molecule to work alongside of